Two types of NHP models of obesity established at KBI
Obesityismajorriskfactorunderlyingdiabetes,cardiovasculardisease(CVD),chronickidneydisease(CKD)andnon-alcoholicsteatohepatitis(NASH),togethertheyimposeserioushealthproblemsworldwide.KunmingBiomedInternational(KBI)hasest
Capacity for the Evaluation of Ophthalmology Gene Therapy at KBI
Retinaleyediseases,suchasdiabeticretinopathyandage-relatedmaculardegeneration,arehighlyprevalentinthemiddle-agedandagedpopulation.Retinalgenetherapyoffersthebesthopeforthesustainedeffectivetreatmentoftheseeyediseaseswit
Chronic Kidney Disease Models in Non-human Primates well Characterized at KBI
ChronicKidneyDisease(CKD)canleadtorenalfailure.CurrentlytheglobalprevalenceofCKDcontinuestoincrease,andithasbecomeamajorcauseofdeathandimposedaheavyburdentothepublichealth.Diabetesandhypertensionarethemajorcausesofthede
KBI Continuous Non-Human Primate (NHP) Cerebrospinal Fluid (CSF) Collection Technology
AccordingtoWHOsreport,morethan1billionpopulationsworldwidesufferfromcentralnervoussystem(CNS)diseasesincludingAlzheimersdisease,multiplesclerosis,epilepsy,Parkinsonsdiseaseandstroke.Despiteenormousefforts,thereisstillno
Scientists discover the beneficial effects of a novel FGF21 analog B1344 on nonalcoholic steatohepatitis in nonhuman primates
TodayKBIannouncethatTheeffectsofB1344,anovelfibroblastgrowthfactor21analog,onnonalcoholicsteatohepatitisinnonhumanprimatespublishedintheprestigiousjournalDIABETES,Dr.ShaohuiJi,scientistformKunmingBiomedInternationalasth
Sanofi Published Research Work Performed in Collaboration with KBI in High Impact Journals
Sanofi,aglobalpharmaceuticalcompanyandlong-termpartnerofKBI,recentlypublishedtheirresearchworkperformedincollaborationwithKBIinhighimpactjournals.ScientistsfromSanofiglobaldiabetesresearchandtranslationalmedicineteamand
Simultaneous quantification of endogenous and exogenous plasma glucose by isotope dilution LC-MS/MS with indirect MRM of the derivative tag
LinglingYu,ChaoWen,XingLi,ShiqiFang,LichuanYang,TonyWang,KaifengHuAbstractQuantificationofendogenousandexogenousplasmaglucosecanhelpmorecomprehensivelyevaluatetheglucosemetabolicstatus.Aratio-basedapproachusingisotopedi
Development and Characterization of High Fat Diet-induced Non-human Primate Models of Liver Diseases:Steatosis, NASH and Fibrosis
CONTROLID:2776800PRESENTATIONTYPE:PosterOnlyCURRENTCATEGORY:SteatosisandSteatohepatitisCURRENTDESCRIPTORS:SO1.Steatohepatitis:ExperimentalTITLE:DevelopmentandCharacterizationofHighFatDiet-inducedNon-humanPrimateModelsof