Diabetic Retinopathy
Diabetic retinopathy (DR) is the eye complication of diabetes. It affects up to 80% of patients who have suffered diabetes for more than 20 years. DR is caused by abnormalities in retinal blood vessels. The retinal vessel changes are initially non-p
Animal Facilities and Capacity
KBI has the state-of-the-art facilities for breeding, housing and research fully compliant with AAALAC and international standards for 8,000 monkeys. The in-door facilities include an SPF barrier unit, a quarantine building, an animal hospital, a nu
Anatomical Pathology
The KBI Section of Anatomic Pathology offers a full range of diagnostic services. Our state-of-the-art technology and sophisticated modalities are available for the critical and accurate assessments of pathology endpoints that are necessary to suppo
Diabetic Nephropathy and Chronic Kidney Disease Models
Diabetic nephropathy (DN) occurs in approximately 20-40% of the type 2 diabetes (T2D) global population. It has always been a challenge to find translatable, reliable and robust animal disease models for diabetic nephropathy − but the monkey mode
Obesity and Metabolic Syndrome
Obesity occurs spontaneously in captive monkeys with similar characteristics to humans in the fat distribution pattern and adipocyte biology. such as pericardial fat which affects cardiac and coronary vasculature functions and central obesity. Centr
Hypertension
KBI has various NHP models of cardiovascular disease including prolonged feeding with high fat diet (HFD), high fat and high fructose diet (HFHFrD) with added cholesterol and spontaneous hypertension with ageing. Hypertension is screened by the meas