KBI has various NHP models of cardiovascular disease including prolonged feeding with high fat diet (HFD), high fat and high fructose diet (HFHFrD) with added cholesterol and spontaneous hypertension with ageing. Hypertension is screened by the measurement of blood pressure (BP) with High Definition Oscillometry (HDO).
HDO is a non-invasive method to measure BP and provides a real-time visualization of oscillometric pulse waves. It as the advantages as follows:
· Fast processors (32 bit)
· High definition sensors
· Easy operation for animals
DO measurement has been validated in comparison to direct BP measurement:
· Normal Systolic Pressure: 110-120 mmHg
· Hypertension: Systolic >140 mmHg
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