Due to the anatomical and functional differences between rodents and humans, reliable large animal models, such as non-human primates, of Spinal Cord Injury (SCI) are critically needed to facilitate translation of laboratory discoveries to clinical applications.

KBI uses a custom-designed large animal spinal cord impactor to develop a SCI model. With successful SCI models, efficacy exploration that will include therapeutic material preparation, dosing route and frequency, efficacy readouts like behavior, lesion volume and special biomarker immunohistochemistry staining can be conducted at KBI.