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Anatomical Pathology

KBI’s Pathology Laboratory offers a full range of diagnostic services with state-of-the-art technology and sophisticated modalities. We routinely use various pathology outcome measures to support our pharmacological efficacy and safety in various NHP disease models. Our capabilities include necropsy, gross pathology examination, organ weight measurement, frozen sections and fixed tissue preparation, light microscopy, immunohistochemistry, immunofluorescent staining and other specialized staining procedures. The capability of our Pathology Laboratory is exemplified in KBI’s successful services for the evaluation of liver steatosis and fibrosis in a number of international NASH studies which have contributed to the translation to clinical trials.


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Fig 1. KBI’s Pathology Laboratory equipped with the state-of-the-art instruments.

Gross Pathology and Necropsy

·  Tissue collection and slices preparation

·  Gross Observations / Clinical Signs Confirmation

·  Perfusion Necropsy (for immunofluorescent staining)

·  Biopsy-Ultrasound-guided or percutaneous

·  Others: Specimens processed by our laboratory include exfoliative cytology specimens (e.g., effusions, ascites, urines, bronchoalveolar lavages, etc.) and biopsy sample.

Histology Capabilities

·  Paraffin section

·  Over-size sample processing and microtomy

·  Special stains

·  Immunohistochemical and immunofluorescence stains

·  Toxicological pathology

·  Interpretation via board-certified pathologists

·  Slide review over the internet

Contact us if you need more information.

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